Asante Kotoko have exited the MTN FA Cup competition after losing 5-4 on penalties to Berekum Chelsea.
The Porcupine Warriors ended the season without a trophy after bowing out of the FA Cup.
This means Kotoko will not take part in any continental football competition next year.
The Reds settled for a goalless stalemate in regulation time after Fabio Gama had missed a penalty.
Chelsea ensured the grabbed a ticket in the last four by converting all five penalty kicks.
Kotoko’s Wahab Adams was a culprit when he missed his kick as the defending Champions bow out of the Cup competition.
Berekum Chelsea sets a date with Ashanti Gold in the semi finals with Medeama also taking on Hearts of Oak in the other semifinals after beating lower tier side Attram d Visser.